National Repository of Grey Literature 16 records found  1 - 10next  jump to record: Search took 0.00 seconds. 
Up-regulation of delayed outwardly rectifying potassium currents in reactive astrocytes after certical stab wound
Anděrová, Miroslava ; Neprašová, H. ; Petřík, D. ; Chvátal, Alexandr ; Syková, Eva
Hypertrophied astrocytes in the close vicinity of the stab wound are characterized by an up-regulation of delayed outwardly rectifying K+ currents and increased K+ accumulation in the vicinity of the astrocyte membrane.
Extracellular space size and geometry in the brain of APP23 mice representing a model of Alzheimer´s disease
Mazel, Tomáš ; Antonova, Tatiana ; Meyer-Luhmann, M. ; Staufenbiel, M. ; Jucker, M. ; Syková, Eva
The decrease in ECS size observed during aging might contribute to increased extracellular amyloid concentration and deposition in APP23 mice.
Alterated diffusion parameters in the brain with kaolin-induced hydrocephalus
Fiala, Jindřich ; Antonova, Tatiana ; Voříšek, Ivan ; Syková, Eva
Compression of the ECS in the cerebral cortex following induction of hydrocephalus, slows down the diffusion of neuroactive substances in hydrocephalic tissue.
Extracellular space volume fraction and geometry in human cortex and glial tumors
Homola, Aleš ; Vargová, Lýdia ; Zámečník, J. ; Tichý, M. ; Beneš, V. ; Syková, Eva
Ecs diffusion parameters in human temporal cortex similar to those previously determined in rat cortex. Volume fraction ? and tortuosity ? are increased in astrocytic gliomas and the higher the glioma´s WHO grade the greater the ECS volume and tortuosity increase. Migration and invasiveness correlate with an increase in ECS volume.
Neuron-glia communication by extrasynaptic transmission
Syková, Eva
Dynamic changes in ECS ionic composition, volume and geometry accompany neuronal activity, neuronal loss, glial development and proliferation, aging, CNS injury, anoxia/ischemia, spreading depression, tumors, inflammation dyemyelination and many other brain pathological states.
Biocompatible polymer hydrogels usable for nervous tissue regeneration
Lesný, Petr ; DeCroos, Jane ; Přádný, Martin ; Vacík, Jiří ; Syková, Eva
PHPMA hydrogel matrices have the ability to induce tissue formation within them and therefore support the regeneration of nervous tissue.
Diffusion and MRS in a rat cortex after traumatic injury
Voříšek, Ivan ; Herynek, V. ; Burian, M. ; Hájek, M. ; Niclay, K. ; Syková, Eva
An increase in diffusion barriers, manifestes by a decrease of both ADCTMA and ADCW, occurs throughout the entire cortex of the wounded hemisphere. These changes are related to astrogliosis and to an accumulation of extracellular matrix molecules without significant changes in ECS volume.
Suppression of 2f1-f2 distortion product otoacoustic emissions by electrical stimulation of the inferior colliculus in guinea pigs
Popelář, Jiří ; Mazelová, Jana ; Syka, Josef
Electrical stimulation of certain parts of the IC resulted in the depression of the DPOAE amplitude by 0.1-2 dB. The value of maximal DPOAE suppression was similar to the DPOAE suppression produced by acoustical stimulation of the contralateral ear. Our results indicate that electrical stimulation of the external cortex of the IC can activate the efferent system and produce DPOAE suppression by similar mechanisms as does acoustical stimulation of the contralateral ear.

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